College of Animal Science & Technology
Northwest A&F University
22 St.XiNong, YangLing, Shaan'xi

Tel: 15091199929

Email: zhangzhy@nwsuaf.edu.cn

           Zzhang888@gmail.com

EDUCATION:

1994-1998 Ph.D.of Biomedicine, Faculty of Veterinary Medicine, University of Montreal.

1982-1985 M.Sc. of Animal Genetics and Breeding, Northwestern Agricultural University, Shaanxi, PRC.

1978-1982 B.Sc. of Animal Genetics and Breeding , Northwestern Agricultural University, Shaanxi, PRC.

RESEARCH INTERESTS:

• Genomics: Application of zinc finger nuclease in generation of transgenic animals and gene function analysis.
• Virology and Oncology. Elucidating mechanisms of the accessory genes of a fish retrovirus (WDSV) inducing skin tumor regression, sponsored by NSRC;

Functional analysis of adenovirus E1A gene in yeast cells, supported by CIHR;

Identification of the mechanism of adenovirus E4orf4 tumor cell killing, supported by CIHR;

● Immunonutrition. Application of immunological nutrition principles to promote animal growth.

POSITIONS HELD:

2008-present  Professor, Northwest A&F University, China

2000-2007 Senior Scientist ,Gemin X Biotechnology Inc., Canada

PATENTS:

1.Title: Antisense calpain nucleotides and uses thereof United States Patent Application: 20040096869 May 20, 2004

Martineau, Daniel; (Saint-Hyacinthe, CA) ; Zhang, Zhiying; (Brossard, CA).       

2.Title:  Diterpenoid compounds, compositions thereof and their use as anti-cancer or anti-fungal agents  United States Patent Application: 20050070540 March 31, 2005

Beauparlant, Pierre; (Montreal, CA) ; Attardo, Giorgio; (Vimont, CA) ; Zhang, Zhiying; (Brossard, CA) ; Stafford, Angela M.; (Castleton, GB) ; Ubillas, Rosa; (Sunnyvale, CA) ; McAlpine, James B.; (Montreal, CA) ; Lavallee, Jean-Francois; (Milles-Iles, CA) ; Fortin, Samuel; (Ste-Luce, CA) ; Tripathy, Sasmita; (Pierrefonds, CA)       

SELECTED PUBLICATIONS:

1. Li S, Brignole C, Marcellus R, Thirlwell S, Binda O, McQuoid MJ, Ashby D, Chan H, Zhang Z, Miron MJ, Pallas DC, Branton PE. The Adenovirus E4orf4 Protein Induces G2/M Arrest and Cell Death by Blocking PP2A Activity Regulated by the B55 Subunit. Journal of Virology, 2009, Jun, 17.
2. Kris S Marshall, Zhiying Zhang, Jennifer Curran, Stephanie Derbyshire and Joe S. Mymryk. 2006, An improved genetic system for detection and analysis of protein nuclear import signals. BMC Molecular Biology. 2007  Jan 25;8:6.
3. Avvakumov. N, M. Sahbegovic, Z. Zhang, M. Shuen and J. Mymryk. 2002, Analysis of DNA binding  by the adenovirus 5 E1A oncoprotein. Journal of General Virology. 2002 Mar;83(Pt 3):517-24.
4. Zhang, Z.  M. Smith and J. Mymryk. 2001, Interaction of the E1A oncoprotein with Yak1p, a novel regulator of yeast pseudohyphal differentiation, and related mammalian kinases.  Mol.  Biol. Cell. 12(3):699-710.

Quick links:

Northwest A & F University: http://www.nwsuaf.edu.cn